Intracellular macrostructure
Cells possess a variety of organelles such as a nucleus, mitochondria, ribosome, and others. We observed that TBC1D24 protein, encoded by the TBC1D24 gene, which...
Bex1 is a juvenile IDP that mediates tubulin polymerization.
Bex1 mediates tubulin polymerization by providing reaction field that enriches GTP to optimize the polymerizing reaction.
We elucidated the new role of Bex1, a juvenile-expressed IDP (intrinsically disordered protein) for the generation of primary cilia. Bex1-KO mice present ciliopathy phenotypes that resemble a ciliopathy, Joubert syndrome.
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JAGs and JALNCs
How are the juvenile properties established in juveniles? Children can grow, learn, adapt, mature, regenerate, and show resilience. Children and adults possess the same sets...Cell competition and juvenility
Cell competition is the competitive relationship among cells. The loser cells of cell competition are eliminated from tissues thereby the tissue integrity is better maintained....
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