Emi Hibino#, Yusuke Ichiyama#, Atsushi Tsukamura#, Yosuke Senju, Takao Morimune, Masahito Ohji, Yoshihiro Maruo, Masaki Nishimura, Masaki Mori*
Bex1 is essential for ciliogenesis and harbors the biomolecular condensate-forming capacity.
(#, equally contributing authors)
BMC Biology, 20, Article number: 42, 2022
Takao Morimune, Ayami Tano, Yuya Tanaka, Haruka Yukiue, Takefumi Yamamoto, Yoshihiro Maruo, Masaki Nishimura, Masaki Mori*
Gm14230 controls Tbc1d24 cytoophidia and neuronal cellular juvenescence.
PLOS One, doi.org/10.1371/journal.pone.0248517, 2021
Faidruz Azura Jam#, Takao Morimune#, Atsushi Tsukamura#, Ayami Tano, Yuya Tanaka, Yasuhiro Mori, Takefumi Yamamoto, Masaki Nishimura, Masaki Mori*
(#, equally contributing authors)
Neuroepithelial cell competition triggers loss of cellular juvenescence.
Scientific Reports, s41598-020-74874-4, 2020
Yosuke Kadota#, Faidruz Azura Jam#, Haruka Yukiue#, Ichiro Terakado, Takao Morimune, Ayami Tano, Yuya Tanaka, Sayumi Akahane, Mayu Fukumura, Masaki Mori*
(#, equally contributing authors)
Srsf7 establishes the juvenile transcriptome through age-dependent alternative splicing in mice.
iScience, doi.org/10.1016/j.isci.2020.100929, 2020
Tempei Sato, Kensuke Kataoka, Yoshiaki Ito, Shigetoshi Yokoyama, Masafumi Inui, Masaki Mori, Satoru Takahashi, Keiichi Akita, Shuji Takada, Hiroe Ueno-Kudoh, et al.
Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates.
eLife, 9:e53608 DOI: 10.7554/eLife.53608, 2020
Ayami Tano#, Yosuke Kadota#, Takao Morimune#, Faidruz Azura Jam, Haruka Yukiue, Jean-Pierre Bellier, Tatsuyuki Sokoda, Yoshihiro Maruo, Masaki Mori*
(#, equally contributing authors)
Juvenility-associated lncRNA Gm14230 maintains cellular juvenescence.
Journal of Cell Science, doi: 10.1242/jcs.227801, 2019
Faidruz Azura Jam#, Yosuke Kadota#, Anarmaa Mendsaikhan#, Masaki Mori*
(#, equally contributing authors)
Identification of juvenility-associated genes in the mouse hepatocytes and cardiomyocytes.
Scientific Reports, 8, 3132, doi:10.1038/s41598-018-21445-3, 2018
Durani L, Hamezah H, Ibrahim F, Yanagisawa D, Nasaruddin M, Masaki Mori, Azizan K, Damanhuri H, Makpol S, Ngah W, Tooyama I.
Tocotrienol-Rich Fraction of Palm Oil Improves Behavioral Impairments and Regulates Metabolic Pathways in AβPP/PS1 Mice.
Journal of Alzheimer Disease, 64, 1, 249-267, 2018
Yokoyama S#, Furukawa S#, Kitada S#, Masaki Mori, Saito T, Kawakami K, Izpisua Belmonte JC, Kawakami Y, Ito Y, Sato T, Asahara H*. (#, equally contributing authors)
Analysis of transcription factors expressed at the anterior mouse limb bud.
PLOS One, May 3, doi.org/10.1371/journal.pone.0175673, 2017
Hongpeng Guan, Hongkuan Yang, Mingchun Yang, Daijiro Yanagisawa, Jean-Pierre Bellier, Masaki Mori, Shogo Takahata, Takashi Nonaka, Shiguang Zhao, Ikuo Tooyama.
Mitochondrial Ferritin protects SH-SY5Y cells against H2O2-induced oxidative stress and modulates alpha-Synuclein expression.
Experimental Neurology, Feb 03; 291:51-61, 2017
Masashi Naito, Masaki Mori, Inagawa M, Miyata K, Hashimoto N, Tanaka S, Asahara H.
Dnmt3a Regulates Proliferation of Muscle Satellite Cells via p57Kip2.
PLOS Genetics, 12(7):e1006167, 2016
Nakamichi R, Ito Y, Inui M, Onizuka N, Kayama T, Kataoka K, Suzuki H, Mori M, Inagawa M, Ichinose S, Lotz M, Sakai D, Masuda K, Ozaki T, Asahara H.
Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs.
Nature Communications, 7:12503, 2016
Tomohiro Kayama, Masaki Mori, Yoshiaki Ito, Takahide Matsushima, Ryo Nakamichi, Hidetsugu Suzuki, Shizuko Ichinose, Mitsuru Saito, Keishi Marumo, Hiroshi Asahara.
Gtf2ird1-dependent Mohawk (Mkx) expression regulates mechanosensing properties of tendon.
Molecular and Cellular Biology, 36(8):1297-309, 2016
Masaki Mori, Robinson Triboulet, Morvarid Mohseni, Karin Schlegelmilch, Kriti Shrestha, Fernando D. Camargo and Richard I. Gregory.
Hippo signaling regulates Microprocessor and links cell density-dependent miRNA biogenesis to cancer
Cell, Volume 156, Issue 5, 893-906, 27 February 2014
Makiko Takeichi, Keisuke Nimura, Masaki Mori, Hironori Nakagami, Yasufumi Kaneda.
The Transcription Factors Tbx18 and Wt1 Control the Epicardial Epithelial-Mesenchymal Transition through Bi-Directional Regulation of Slug in Murine Primary Epicardial Cells
PLoS ONE 8(2): e57829. doi:10.1371/journal.pone.0057829, February, 2013
Masaki Mori, Hironori Nakagami, Gerardo Rodriguez-Araujo, Keisuke Nimura, Yasufumi Kaneda.
Essential Role for miR-196a in Brown Adipogenesis of White Fat Progenitor Cells.
PLoS Biology 10(4): e1001314. doi:10.1371/journal.pbio.1001314, April, 2012
Gerardo Rodriguez-Araujo, Hironori Nakagami, Hiroki Hayashi, Masaki Mori, Tetsuya Shiuchi, Yasuhiko Minokoshi, Yoshikazu Nakaoka, Yoichi Takami, Issei Komuro, Ryuichi Morishita, Yasufumi Kaneda.
Alpha-synuclein elicits glucose uptake and utilization in adipocytes through the Gab1/PI3K/Akt transduction pathway
Cellular and Molecular Life Sciences; 10.1007/s00018-012-1198-8, March, 2012
Hiroki Hayashi, Hironori Nakagami, Makiko Takeichi, Munehisa Shimamura, Nobutaka Koibuchi, Eiji Oiki, Naoyuki Sato, Hiroshi Koriyama, Masaki Mori, Rodriguez Gerardo Araujo, Akito Maeda, Ryuichi Morishita, Katsuto Tamai and Yasufumi Kaneda.
HIG1, a novel regulator of mitochondrial r-secretase, maintains normal mitochondrial function
The FASEB Journal; vol. 26, no. 6, 2306-2317, June, 2012
Koji Hatano, Yasuhide Miyamoto, Masaki Mori, Keisuke Nimura, Yasutomo Nakai, Norio Nonomura, Yasufumi Kaneda.
Androgen-Regulated Transcriptional Control of Sialyltransferases in Prostate Cancer Cells.
PLoS ONE 7(2): e31234. doi:10.1371/journal.pone.0031234, February, 2012
Masaki Mori, Hironori Nakagami, Nobutaka Koibuchi, Koichi Miura, Yoichi Takami, Hiroshi Koriyama, Hiroki Hayashi, Hisataka Sabe, Naoki Mochizuki, Ryuichi Morishita, and Yasufumi Kaneda.
Zyxin Mediates Actin Fiber Reorganization in Epithelial–Mesenchymal Transition and Contributes to Endocardial Morphogenesis.
Molecular Biology of the Cell Vol. 20, 3115–3124, July 1, 2009
(第73回日本循環器学会、第4回小児循環器賞受賞論文)
Nakagami Hironori, Osako Miana Kiyomi, Takami Yoichi, Hanayama Rie, Koriyama Hiroshi, Mori Masaki, Hayashi Hiroki, Shimizu Hideo, Morishita Ryuichi.
Vascular protective effects of ezetimibe in ApoE-deficient mice.
Atherosclerosis Mar;203(1):51-8, 2009
Hiroki Hayashi, Hironori Nakagami, Yoichi Takami, Hiroshi Koriyama, Masaki Mori, Katsuto Tamai, Jianxin Sun, Kaori Nagao, Ryuichi Morishita, Yasufumi Kaneda.
FHL-2 Suppresses VEGF-Induced Phosphatidylinositol 3-Kinase/Akt Activation via Interaction With Sphingosine Kinase-1.
Arteriosclerosis, Thrombosis, and Vascular Biology. 29:909, June, 2009
Yoichi Takami, Hironori Nakagami, Ryuichi Morishita, Tomohiro Katsuya, Hiroki Hayashi, Masaki Mori, Hiroshi, Koriyama, Yoshichika Baba, Osamu Yasuda, Hiromi Rakugi, Toshio Ogihara, Yasufumi Kaneda.
Potential Role of CYLD (Cylindromatosis) as a Deubiquitinating Enzyme in Vascular Cells.
The American Journal of Pathology; 172, 818-829, March, 2008
Nakagami Hironori, Osako Mariana Kiyomi, Takami Yoichi, Hanayama Rie, Koriyama Hiroshi, Masaki Mori, Hayashi Hiroki, Shimizu Hideo, Morishita Ryuichi.
Differential response of vascular hepatocyte growth factor concentration and lipid accumulation between telmisartan and losartan in ApoE-deficient mice.
Molecular Medicine Reports. (5):657-61. doi: 10.3892/mmr_00000008. Sep-Oct;1, 2008
Hiroki Hayashi, Hironori Nakagami, Yoichi Takami, Naoyuki Sato, Yukihiro Saito, Tomoyuki Nishikawa, Masaki Mori, Hiroshi Koriyama, Katsuto Tamai, Ryuichi Morishita, Yasufumi Kaneda.
Involvement of γ-secretase in Postnatal Angiogenesis.
Biochemical and Biophysical Research Communication; 363, 584-590, November, 2007
Masaki Mori, Hironori Nakagami, Ryuichi Morishita, Naoyuki Sato, Toshio Ogihara, Yasufumi Kaneda.
N141I Mutant Presenilin-2 Gene Enhances Neuronal Cell Death and Decreases Bcl-2 Expression.
Life Sciences; 70, 2567-2580, April, 2002